Feedback Inhibition of Amidophosphoribosyltransferase Regulates the Rate of Cell Growth via Purine Nucleotide, DNA, and Protein Syntheses

This publication has 21 references indexed in Scilit:

• Methotrexate inhibits the first committed step of purine biosynthesis in mitogen-stimulated human T-lymphocytes: a metabolic basis for efficacy in rheumatoid arthritis?
  Biochemical Journal, 1999
• Hypoplasia of pancreatic islets in transgenic mice expressing activin receptor mutants.
  Journal of Clinical Investigation, 1998
• Importance of Ribonucleotide Availability to Proliferating T-lymphocytes from Healthy Humans
  Journal of Biological Chemistry, 1995
• The genetic and functional basis of purine nucleotide feedback-resistant phosphoribosylpyrophosphate synthetase superactivity.
  Journal of Clinical Investigation, 1995
• Efficient selection for high-expression transfectants with a novel eukaryotic vector
  Gene, 1991
• The proteins encoded by the VpreB and lambda 5 pre-B cell-specific genes can associate with each other and with mu heavy chain.
  The Journal of Experimental Medicine, 1990
• Biochemical genetics of Chinese hamster cell mutants with deviant purine metabolism: Characterization of Chinese hamster cell mutants defective in phosphoribosylpyrophosphate amidotransferase and phosphoribosylglycinamide synthetase and an examination of alternatives to the first step of purine biosynthesis
  Somatic Cell and Molecular Genetics, 1977
• De novo synthesis of purine nucleotides in human peripheral blood leukocytes. Excessive activity of the pathway in hypoxanthine-guanine phosphoribosyltransferase deficiency.
  Journal of Clinical Investigation, 1976
• A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
  Analytical Biochemistry, 1976
• IMMUNOLOGICAL OBSERVATIONS ON PATENTS WITH LESCH-NYHAN SYNDROME, AND ON THE ROLE OF DE-NOVO PURINE SYNTHESIS IN LYMPHOCYTE TRANSFORMATION
  The Lancet, 1975