The secretion of pituitrin in mammals, as shown by perfusion of the isolated kidney of the dog

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Abstract
Organs of internal secretion may conveniently be considered as belonging to one of two groups. In the one the secretory product is continuously being poured into the circulation, the physiological condition which we are pleased to call normal being dependent on this occurrence for its very maintenance. In the other group secretory activity is called into play only in conditions of stress when the normal physiological balance is upset to an abnormal degree, the extent of the activity being delimited by the return of the organism to its previous physiological condition.

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