Cimetidine and Polymyositis

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Abstract
To the Editor: Watson et al. recently reported a case of polymyositis induced by cimetidine, a drug with a possible role as an immunomodulator (Jan. 20 issue).1 Since November 1982, we have had the opportunity to follow the patient described in their report and wish to provide follow-up data that argue against the role of cimetidine in inducing polymyositis in this patient.Although cimetidine had been discontinued in January 1982, the patient had active myositis when first seen by us. In January 1983, while taking prednisone (60 mg per day) and mercaptopurine (50 mg three times a day), he had . . .