SPONTANEOUS AND EXPERIMENTAL INFECTIONS OF XENOPUS-LAEVIS WITH CHLAMYDIA-PSITTACI

1 January 1982

journal article
research article

Vol. 32 (6) , 680-686

Abstract

Chlamydial infection was suspected when widespread pyogranulomatous inflammation and large basophilic intracytoplasmic inclusion bodies were evident histopathologically in African clawed frogs (X. laevis) dying of a spontaneous disease of high morbidity and mortality. Organism morphology was determined by EM of infected hepatic sinusoidal lining cells, and it was characteristic of the unique developmental cycle of a chlamydial agent. Isolation and speciation of the organism was achieved in a mouse McCoy cell culture system. The infected cells were inoculated into disease-free frogs reproducing the disease.

This publication has 1 reference indexed in Scilit:

Factors affecting the rate as which a trachoma strain of Chlamydia trachomatis establishes persistent infections in mouse fibroblasts (McCoy cells)
Infection and Immunity, 1981