Moebius syndrome

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Abstract
SUMMARYA patient has been described with Moebius syndrome in whom there was clinical paralysis of the muscles supplied by the third, fourth, sixth, and seventh cranial nerves. Limb muscle biopsy studies and electromyography of the limb muscle suggest denervation of an “anterior horn cell” type of abnormality in the spinal cord. Moebius was also of the opinion that the syndrome was secondary to lower motor neuron abnormality and that the cord could be involved. The hypogonadism of our patient was secondary to a deficiency of gonadotropic hormone.

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