Elastic model of supercoiling.
- 1 June 1977
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 74 (6) , 2397-2401
- https://doi.org/10.1073/pnas.74.6.2397
Abstract
An elastic model for the supercoiling of duplex DNA is developed. The simplest assumptions regarding the elastic properties of double-helical DNA (homogeneous, isotropic, of circular cross section and remaining straight when unstressed) will generate 2 orders of superhelicity when stressed. Recent experimental results suggest that in supercoiled DNA molecules there are regions where 2 distinct orders of supercoiling arise, as predicted by this model.Keywords
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