MEDICO-GENETIC STUDY OF ISOLATES IN UZBEKISTAN .1. STATEMENT OF PROBLEM AND CHARACTERISTICS OF EXAMINED GROUPS

  • 1 January 1975
    • journal article
    • research article
    • Vol. 11  (11) , 90-99
Abstract
Demographic and population characteristics were studied of the inhabitants of the Samarkand region [USSR] as a whole and 2 villages, Karakent and Ishan, inhabited by Uzbeks-Khoja, a special religious-social caste. In the Samarkand region 87.4% of marriages are of international character. The frequency of consanguineous marriages is 11.6%, and among them 40.5% are 1st-cousin marriages and 39.1% are marriages of remote relatives. The coefficients of inbreeding are rather high among the Jewish, Tajik and Uzbek communities. The coefficient of inbreeding as a whole is F = 0.0042 in this region and approaches to the maximal level, characterizing a panmix population. The average size of a family in the villages of Karakent and Ishan is approximately 4.0 persons. The values of reproductive performance and the nature of termination of pregnancies do not differ from those of panmix population. The percentage of intravillage and consanguineous marriages are 56% and 12.5% for the 1st village, and 25% and 2% for the second, respectively. The coefficient of inbreeding for Karakent is F = 0.0064, for Ishan, F = 0.0014. Taking into consideration the historical development of the 2 villages and the cumulative data, Karakent is an isolate on a religious ground whereas Ishan is a disintegrated isolate.

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