Tetracycline and minocycline treatment
- 1 January 1982
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 118 (1) , 19-22
- https://doi.org/10.1001/archderm.118.1.19
Abstract
The effect of 1000 mg of tetracycline hydrochloride and 200 mg of minocycline hydrochloride on P. acnes levels and skin-surface lipid levels was measured in 15 patients with acne. Minocycline produced a significantly greater reduction in the P. acnes counts that persisted even up to 3 wk after discontinuation of the minocycline therapy, in contrast to the return of P. acnes to baseline counts within 3 wk after discontinuation of the tetracycline therapy. A similar persistence of effect for reduction of skin-surface free fatty acid levels and clinical lesions was also seen with minocycline therapy.This publication has 3 references indexed in Scilit:
- Regional variations of cutaneous propionibacteriaApplied and Environmental Microbiology, 1978
- Acne vulgaris: an investigation into the number of anaerobic diphtheroids and members of Micrococcaceae the in normal and acne skinBritish Journal of Dermatology, 1977
- A New Method for the Quantitative Investigation of Cutaneous Bacteria*Journal of Investigative Dermatology, 1965