Genetic effects of 1,2‐dibromo‐3‐chloropropane (DBCP) in drosophila
- 1 January 1982
- journal article
- research article
- Published by Wiley in Environmental Mutagenesis
- Vol. 4 (6) , 681-687
- https://doi.org/10.1002/em.2860040607
Abstract
Induction of sex‐linked recessive lethal mutations, heritable translocations and genetic crossing‐over were studied in Drosophila melanogaster males treated as adults and as embryos with different concentrations of gaseous DBCP. Adults exposed to 30 ppm/hr of the compound did not produce a significant number of sex‐linked recessive lethal mutations in treated spermatozoa, spermatids, or spermato‐cytes. However, at an exposure of 17.7 ppm/hr, a weak mutagenic effect was observed in embryonic spermatogonia. No translocation was scored in 4032 tested chromosomes from adults treated with 150 ppm/hr. However, a significant number of spermatocytial crossovers were induced after an exposure of 120 ppm/hr.Keywords
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