Fortnightly review: Modern drug treatment of chronic asthma

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Abstract
Methods I searched Medline and BIDS for articles published between 1977 and 1998, using appropriate index terms for each drug or class of drugs. I included key review articles and searched manually for relevant papers and abstracts in recent issues of mainstream journals on general, respiratory, and allergy medicine. This article was also based on personal, long standing, clinical and research interests in the management of allergy and asthma. Some aspects of this review will inevitably be based on personal opinion, particularly where the latest guidelines are already out of date—for example, with the emerging role of leukotriene antagonists. View larger version: In this window In a new window Fig 1 The inflammatory cascade in asthma