Chromosome assignment and restriction fragment length polymorphism analysis of the anonymous DNA probe B79a at 7q22 (HMG8 assignment D7S13)
- 1 November 1986
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 74 (3) , 320-322
- https://doi.org/10.1007/bf00282558
Abstract
The anonymous DNA fragment B79a, which had previously been located to chromosome 7cen-7q22, has been more accurately assigned to 7q22 by dosage analysis in a patient hemizygous for a deletion of that region. By examination of a panel of genomic DNAs from unrelated individuals, digested with a number of different restriction enzymes, we have identified two frequent RFLPs detected by B79a. This probe will be important in the analysis of cystic fibrosis which has been mapped to the region around 7q22.Keywords
This publication has 12 references indexed in Scilit:
- Localisation of a sequence, 7C22, showing close linkage to the cystic fibrosis locusCytogenetic and Genome Research, 1987
- Cystic fibrosis carrier detection using a linked gene probe.Journal of Medical Genetics, 1986
- FIRST-TRIMESTER PRENATAL DIAGNOSIS OF CYSTIC FIBROSIS WITH LINKED DNA PROBESThe Lancet, 1986
- LINKAGE OF COL1A2 COLLAGEN GENE TO CYSTIC FIBROSIS, AND ITS CLINICAL IMPLICATIONSThe Lancet, 1985
- Cystic Fibrosis Locus Defined by a Genetically Linked Polymorphic DNA MarkerScience, 1985
- The human met oncogene is related to the tyrosine kinase oncogenesNature, 1985
- Localization of cystic fibrosis locus to human chromosome 7cen–q22Nature, 1985
- A closely linked genetic marker for cystic fibrosisNature, 1985
- Linkage relationships of paraoxonase (PON) with other markers: indication of PON‐cystic fibrosis syntenyClinical Genetics, 1985
- Analysis of human Y-chromosome-specific reiterated DNA in chromosome variants.Proceedings of the National Academy of Sciences, 1977