Trifluoromethylated furans via iodocyclisation of γ-unsaturated ethyl trifluoroacetoacetates
- 1 January 1993
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 22,p. 2787-2791
- https://doi.org/10.1039/p19930002787
Abstract
Under iodoetherification conditions, γ-unsaturated ethyl trifluoroacetoacetates 1a–c exhibit a specific reactivity. Conditions were found for the synthesis of cyclic iodo hemiketals 2a–c and for their subsequent conversion into either α-trifluoromethylated furans or trifluoromethylated dioxabicyclo[2.2.1]heptanes.Keywords
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