Immunological, histological and electron-microscopical lnvestigations of the gut in atopic dermatitis

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Abstract
Jejunal biopsy specimcns were obtained from ten patients with severe atopic dermatitis and 15 controls. Light microscopical examination of hematoxylin-eosin stained sections showed normal condition in all atopic patients and intra-epithelial lymphocyte counts did not differ significantly from counts in controls. Scanning electron-microscopical examination demonstrated minor mucosal changes in five of the atopic patients. Immunohistochemical studies did not reveal any significant changes in the class proportions and numbers or jejunal immunoglobulin-producing cells.

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