Detection by 1H-NMR Spectroscopy of Chloroquine in Urine from Acutely Poisoned Patient
- 1 April 1997
- journal article
- research article
- Published by Oxford University Press (OUP) in Clinical Chemistry
- Vol. 43 (4) , 698-699
- https://doi.org/10.1093/clinchem/43.4.698
Abstract
High-resolution NMR spectroscopy is increasingly being used to analyze a variety of physiological fluids (1)(2) and may constitute a new tool in clinical diagnosis. Many important low-molecular-mass metabolites can be readily detected and quantified by 1H-NMR. New sequences, such as 1H–1H J-resolved map, have proved very useful (3). We have used these methods to investigate a urine sample obtained in a case of acute chloroquine poisoning.Keywords
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