Oxygen Sensing Gets a Second Wind
- 1 February 2002
- journal article
- editorial
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 295 (5556) , 807-808
- https://doi.org/10.1126/science.1069825
Abstract
The recent discovery of molecules that mediate the hypoxia response pathway demonstrates that mammalian cells are supremely well adapted to dealing with conditions of low oxygen. In their Perspective, Bruick and McKnight detail new findings ( Lando et al.) that describe an additional way in which the transcription factor HIF, a central player in the hypoxia response pathway, can be regulated.Keywords
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