Inhibition of lipid peroxidation by the iron-binding protein lactoferrin
- 1 October 1981
- journal article
- research article
- Published by Portland Press Ltd. in Biochemical Journal
- Vol. 199 (1) , 259-261
- https://doi.org/10.1042/bj1990259
Abstract
Lactoferrin containing physiological amounts of iron is an inhibitor of lipid peroxidation induced by iron(III) salts and ascorbic acid. It might therefore help to protect neutrophils, inflammatory foci and secretions from metal-ion-dependent oxidative damage.This publication has 13 references indexed in Scilit:
- Superoxide-dependent formation of hydroxyl radicals in the presence of iron salts. Detection of ‘free’ iron in biological systems by using bleomycin-dependent degradation of DNABiochemical Journal, 1981
- Lactoferrin enhances hydroxyl radical production by human neutrophils, neutrophil particulate fractions, and an enzymatic generating system.Journal of Clinical Investigation, 1981
- Iron in human milkThe Journal of Pediatrics, 1980
- Isolation of lactoferrin from human whey by a single chromatographic stepFEBS Letters, 1980
- The production of hydroxyl and superoxide radicals by stimulated human neutrophils — measurements by EPR spectroscopyFEBS Letters, 1979
- Oxygen-Dependent Microbial Killing by PhagocytesNew England Journal of Medicine, 1978
- The measurement of malondialdehyde in peroxidised ox-brain phospholipid liposomesAnalytical Biochemistry, 1977
- Evidence for superoxide-dependent reduction of Fe3+ and its role in enzyme-generated hydroxyl radical formationChemico-Biological Interactions, 1976
- The effect of serum and experimental variables on the transferrin and reticulocyte interactionBiochimica et Biophysica Acta (BBA) - General Subjects, 1975
- Metal‐Combining Properties of Human Lactoferrin (Red Milk Protein)European Journal of Biochemistry, 1968