Cucurbitacins and cucurbitane glycosides: structures and biological activities
Top Cited Papers
- 4 April 2005
- journal article
- review article
- Published by Royal Society of Chemistry (RSC) in Natural Product Reports
- Vol. 22 (3) , 386-399
- https://doi.org/10.1039/b418841c
Abstract
Covering: 1980 to August 2004 The natural cucurbitacins constitute a group of triterpenoid substances which are well-known for their bitterness and toxicity. Structurally, they are characterized by the tetracyclic cucurbitane nucleus skeleton, namely, 19-(10→9β)-abeo-10α-lanost-5-ene (also known as 9β-methyl-19-norlanosta-5-ene), with a variety of oxygen substitutions at different positions. According to the characteristics of their structures, cucurbitacins are divided into twelve categories. The biological effects of the cucurbitacins are also covered.Keywords
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