ELECTROPHORETIC ANALYSIS OF THE PROTEINS OF PLASMA AND SEROUS EFFUSIONS

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Abstract
The proteins of plasma and serous effusions were compared in the electrophoresis apparatus of Tiselius. The same protein fractions found in plasma were seen in effusion fluids. The proportion of albumin was invariably higher in effusion than in plasma. Effusions due to cardiac failure contained relatively more albumin than those due to inflammation or neoplasm. [BETA]-globulin and fibrinogen were relatively lower in effusions than in plasma, presumably due in the case of [BETA]-globulin to its association with colloidal particles of lipid, and in the case of fibrinogen to the defibrinating action of the serosa. With these modifications, the distr. of protein fractions in effusions clearly reflected any changes in plasma proteins.