New Tandem Catalysis: Preparation of Cyclic Enol Ethers through a Ruthenium-Catalyzed Ring-Closing Metathesis−Olefin Isomerization Sequence
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- 16 October 2002
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of the American Chemical Society
- Vol. 124 (45) , 13390-13391
- https://doi.org/10.1021/ja028044q
Abstract
Tandem reactions that proceed with a single metal catalyst precursor offer novel opportunities for developing efficient new reaction sequences. In this regard, reaction conditions have been identified that allows for a tandem ring-closing metathesis−olefin isomerization sequence catalyzed by a common ruthenium precursor. Specifically, the tandem process generates cyclic enol ethers from a variety of readily available acyclic dienes in a single reaction vessel using Grubbs' ruthenium alkylidene.Keywords
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