Alopecia totalis does not respond to the vitamin-D analogue calcipotriol
- 1 January 1991
- journal article
- research article
- Published by Taylor & Francis in Journal of Dermatological Treatment
- Vol. 1 (6) , 293-294
- https://doi.org/10.3109/09546639109086760
Abstract
The vitamin-D analogue calcipotriol has immunological properties which suggest that it may be effective in alopecia areata. To investigate this we assessed the response to treatment with this compound in a group of 20 patients with alopecia totalis or universalis. The study was of placebo-controlled double-blind design. Each subject applied ointment containing 50 μg/g calcipotriol to one side of the scalp and matching vehicle to the other. There was no evidence of a response to calcipotriol in this group of subjects with very severe alopecia.Keywords
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