Age differences and stress ulcer in the rat
- 1 February 1979
- journal article
- research article
- Published by Taylor & Francis in Experimental Aging Research
- Vol. 5 (1) , 31-42
- https://doi.org/10.1080/03610737908257186
Abstract
Rats 2-, 7- and 12- mo. old were exposed to supine body restraint plus cold (5°C) for 3 hr. The mean cumulative length of lesions for the 2-, 7-, and 12 mo. old rats was 22.0, 43.0 and 16.0 mm. respectively. The same experimental design was used in a second study, but the pylorus was ligated prior to restraint. Total acid output/hr. was 134.6, 178.2, and 64.7 μEq/60 min. respectively for the three age groups. Older rats were not more susceptible to stress-ulcer and gastric acid was not significantly related to degree of ulceration.This publication has 19 references indexed in Scilit:
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