Insulin treatment in children and adolescents
- 1 April 2004
- journal article
- review article
- Published by Wiley in Acta Paediatrica
- Vol. 93 (4) , 440-446
- https://doi.org/10.1080/08035250410024934
Abstract
The management of diabetes in children presents a number of challenges. The ideal is to achieve optimal glycaemic control using an insulin regimen that is acceptable to the child and family, which improves glycaemic control, whilst avoiding hypoglycaemia. The paediatric population differ from their adult counterparts in several ways, such as variability of exercise and eating patterns, and the hormonal influences of puberty, which means that the insulin regimen must be tailored to suit an individual child and their family. Conclusion: This review will focus on the particular difficulties of managing diabetes in children and, in particular, the problem of avoiding hypoglycaemia while maintaining adequate glycaemic control.Keywords
This publication has 47 references indexed in Scilit:
- Insulin lispro: a potential role in preventing nocturnal hypoglycaemia in young children with diabetes mellitusDiabetic Medicine, 2003
- Insulin injection regimens and metabolic control in an international survey of adolescents with type 1 diabetes over 3 years: results from the Hvidore study groupEuropean Journal of Pediatrics, 2003
- Beneficial effects of intensive therapy of diabetes during adolescence: Outcomes after the conclusion of the Diabetes Control and Complications Trial (DCCT)The Journal of Pediatrics, 2001
- Counterregulation during spontaneous nocturnal hypoglycemia in prepubertal children with type 1 diabetes.Diabetes Care, 1999
- Hypoglycaemia leads to an increased QT interval in normal menClinical Physiology and Functional Imaging, 1998
- Effect of Fatty Acids and Selected Drugs on the Albumin Binding of a Long-Acting, Acylated Insulin AnalogueJournal of Pharmaceutical Sciences, 1997
- Injection Site Effects on the Pharmacokinetics and Glucodynamics of Insulin Lispro and Regular InsulinDiabetes Care, 1996
- Effect of intensive diabetes treatment on the development and progression of long-term complications in adolescents with insulin-dependent diabetes mellitus: Diabetes Control and Complications TrialThe Journal of Pediatrics, 1994
- Exaggerated epinephrine responses to hypoglycemia in normal and insulin-dependent diabetic childrenThe Journal of Pediatrics, 1987
- Reduction to Normal of Plasma Glucose in Juvenile Diabetes by Subcutaneous Administration of Insulin with a Portable Infusion PumpNew England Journal of Medicine, 1979