Two Novel Vaginal Microbicides (Polystyrene Sulfonate and Cellulose Sulfate) InhibitGardnerella vaginalisand Anaerobes Commonly Associated with Bacterial Vaginosis

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Abstract
This is the first report demonstrating the in vitro inhibitory activity of two novel microbicides (cellulose sulfate and polystyrene sulfonate) against bacterial vaginosis (BV)-associated bacteria. Vaginal application of these microbicides not only may reduce the risk of acquisition of human immunodeficiency virus and other sexually transmitted infection-causing organisms but may also decrease the incidence of BV.