TREATMENT OF EWING SARCOMA WITH HIGH-DOSE MELPHALAN AND AUTOLOGOUS BONE-MARROW TRANSPLANTATION

  • 1 January 1981
    • journal article
    • research article
    • Vol. 65  (3-4) , 241-244
Abstract
Three patients with disseminated, relapsed Ewing''s sarcoma refractory to conventional chemotherapy were treated with high-dose melphalan, cyclophosphamide pretreatment and bone marrow autotransplantation. Two patients achieved complete remission and 1 achieved partial remission. The 2 patients who achieved complete remission remain disease-free at 12 and 13 mo. High-dose melphalan is effective when conventional approaches have failed.