Determination of Some Tetracyclines Spectrophotometrically by Flow Injection Analysis
- 1 October 1992
- journal article
- research article
- Published by Taylor & Francis in Analytical Letters
- Vol. 25 (10) , 1865-1876
- https://doi.org/10.1080/00032719208018259
Abstract
A spectrophotometric method for the determination of some tetracyclines is described. The suggested method is based on the reaction of the drug with sodium tungstate at pH 6 to form a yellow complex which can be determined spec trophotometrically. The complexes show absorption maxima at 380, 3385 and 390 nm for oxytetracycline hydrochloride(OTCH), doxycycline hydrochloride(DCH) and chlortetracycline hydro-chloride(CTCH), respectively. These drugs can be determined either in pure form or in pharmaceutical preparations.Keywords
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