Abstract
A quantitative comparison of the activity of six penicillins against Escherichia coli has been made. The order of their effectiveness in inhibiting growth was benzylpenicillin and phenbenicillin, phenoxy-methylpenicillin, phenethicillin, propicillin, methicillin; and in inducing spheroplasts benzylpenicillin, phenoxymethylpenicillin, phenethicillin and phenbenicillin, propicillin, methicillin.

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