Beta Cell Protection to Alloxan Necrosis by Anomers of D-Glucose
- 1 February 1974
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 183 (4123) , 424
- https://doi.org/10.1126/science.183.4123.424
Abstract
Various concentrations of either the α or β anomers of D-glucose were injected into fasted rats prior to a diabetogenic dose of alloxan. Plasma concentrations of glucose were measured 24 hours later. There was a significantly greater protection of the pancreatic beta cells by the α anomer of D-glucose as compared to the β anomer, which was evidenced by concentrations of glucose in the plasma, and morphology of beta cells.Keywords
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