Application of Cyclodextrins in the Chromatography

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Abstract
The central cavity of the cylinder‐shaped cyclodextrin molecules behaves as an empty molecular capsule: it can accomodate so called ‘guest molecules’ of appropriate size, shape and polarity. The stability of the formed inclusion complexes is however very different. This is the basis of the separation of various substances by cyclodextrins. The separation can be realized by non‐chromatographic methods or by chromatographic methods. The present review summarizes the utilization of cyclodextrins and their derivatives in gas‐liquid and gas‐solid‐, gel‐, inclusion‐, thin‐layer‐, affinity‐, and high performance liquid chromatography.