Some Measurements of Protection against Paratyphoid Salmonella and Escherichia coli by Competitive Exclusion in Chickens

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Abstract
The crop and cecum were the major sites of Salmonella colonization. A technique to determine the possible adherence of Salmonella to the epithelial wall of the cecum demonstrated that Salmonella adhered firmly. Protection following introduction of the native gut microflora began within 2 h post-treatment; optimum protection was not established until 32 h post-treatment. The protection of chickens afforded by native gut microflora against combined challenge by S. typhimurium and pathogenic E. coli (O138) was demonstrated.