Serum Beta-Lipoprotein Subfractions in Polyacrylamide Gel Electrophoresis Associated with Coronary Heart Disease
- 1 January 1976
- journal article
- research article
- Published by Taylor & Francis in Scandinavian Journal of Clinical and Laboratory Investigation
- Vol. 36 (1) , 75-79
- https://doi.org/10.3109/00365517609068021
Abstract
Subfractions of β-lipoprotein occurred more frequently in serum from patients with coronary heart disease than in serum from patients with no sign of coronary heart disease. Two β-lipoprotein subfractions were observed in polyacrylamide gel electrophoresis. The sera containing a β-lipoprotein sub-fraction with a position close to the β-lipoprotein band showed Lp(a) antigenic properties. Triglycerides were raised in the sera with β-lipoprotein subfractions. The cholesterol level was significantly higher in the coronary heart disease group but was not correlated to the presence of the β-lipoprotein subfraction. The β-lipoprotein subfraction may possibly represent an additional risk factor in the genesis of coronary heart disease, even in the absence of other hyperlipoproteinemias.Keywords
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