SUPPOSED ROLE OF THE ADRENALS IN HYPERTENSION
- 25 June 1938
- journal article
- research article
- Published by American Medical Association (AMA) in JAMA
- Vol. 110 (26) , 2127-2132
- https://doi.org/10.1001/jama.1938.02790260001001
Abstract
Our experiments constitute part of an investigation on the alleged relation of the adrenal medulla to certain diseases, particularly diabetes mellitus and hypertension. The supposition of such a relation is a basis for the clinical practice of surgical intervention at the adrenals or roentgen irradiation of the adrenal region as a therapeutic measure. Therefore it is important to determine if possible whether this alleged relationship can be supported by unequivocal experimental evidence. The prevailing concept that increased epinephrine secretion from the adrenal glands has an important role in the etiology and the pathology of hypertension rests largely on the experimental basis for the theory of an "emergency" function of the adrenals. In a discussion of their experiments on epinephrine secretion during emotional excitement, on which the well known emergency theory rests, Cannon and de la Paz1stated: Injected epinephrine is capable of inducing an atheromatous condition of the arterialKeywords
This publication has 1 reference indexed in Scilit:
- The control of the suprarenal glands by the splanchnic nerves1The Journal of Physiology, 1912