GLYCOGEN IN THE NORMAL HUMAN TESTIS: A HISTOCHEMICAL AND HISTOENZYMATIC STUDY

Abstract
SUMMARY Histological and histochemical investigations were carried out on the testes of normal subjects in order to define the distribution of glycogen and some related enzymes. Intratubular glycogen is abundant in the prepubertal stage; it diminishes strikingly with the beginning of puberty, reappears during the period of complete sexual maturation, and the highest increase is found in the tubules in involution. Glycogen is abundant at some stages of spermatogenesis and almost completely absent in others. Glycogen is mainly, but not exclusively, localized in the Sertoli cells. 1–4 Amylophosphorylase and 1–4, 1–6 transglucosidase are present in the tubule as well as in some extratubular structures. It is not possible to demonstrate the presence of either UDPG-glycogen transferase or glucose-6-phosphatase.

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