Recovery of rat gastric mucosa following single fluoride dosing
- 1 November 1985
- journal article
- research article
- Published by Wiley in Journal of Oral Pathology & Medicine
- Vol. 14 (10) , 779-792
- https://doi.org/10.1111/j.1600-0714.1985.tb00468.x
Abstract
Rats' stomachs were intubated with 0.1 N HCl or 100 mM NaF in 0.1 N HCl and excised after 1, 12, 24, 48 h or 7 days for light microscopy. The NaF solution caused erosive injury to the oxyntic glandular mucosa 1 h after application. Progressive stages of recovery were seen at 12, 24 and 48 h after fluoride dosing. Complete recovery was seen 7 days after exposure to fluoride. The kinetics of the recovery process from fluoride injury appear to he similar to those which have been reported for gastric injury produced by other substances.This publication has 23 references indexed in Scilit:
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