HYPOPHYSIS IN PROTEIN METABOLISM. IS THE PITUITARY FACTOR ACTIVE IN PROTEIN METABOLISM IDENTICAL WITH THE GROWTH HORMONE?
- 1 September 1938
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 23 (3) , 368-370
- https://doi.org/10.1210/endo-23-3-368
Abstract
The protein metabolism hormone of the pituitary lowers the blood amino-N and the blood urea-N level of rats, dogs and guinea-pigs after adm. of alkaline pituitary extracts. It prevents the rise of blood-amino acids if, 3 hrs. after a 1st adm. of 50 gm. of gelatine, a 2d adm. of the same quantity follows. This is the "regulation effect" in protein metabolism. In 3 cases of Simonds''s pituitary cachexia this regulation effect was missing. In 2 cases of pituitary nanosomia the regulation effect was normal. This was considered proof that the protein metabolism hormone was not identical with the growth hormone.This publication has 1 reference indexed in Scilit:
- THE EFFECT OF EXTRACTS CONTAINING THE GROWTH PRINCIPLE OF THE ANTERIOR HYPOPHYSIS UPON THE BLOOD CHEMISTRY OF DOGSAmerican Journal of Physiology-Legacy Content, 1929