Polyene antibiotic affinities for the sterols of resistant and sensitive strains of Neurospora crassa
- 1 January 1977
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Microbiology
- Vol. 23 (1) , 113-115
- https://doi.org/10.1139/m77-015
Abstract
Ergosterol, the principle sterol of many wild-type Neurospora and other Ascomycetes, had a greater affinity for polyene antibiotics than did lichesterol or eburicol, the sterols of some resistant mutant strains. The affinity was demonstrated by comparing the sterols extracted from sensitive and resistant strains of Neurospora crassa and Candida albicans for protection against polyene inhibition of sensitive N. crassa and for their ability to alter specific polyene absorption maxima.This publication has 1 reference indexed in Scilit:
- Free and bound lipids of Neurospora crassaPhytochemistry, 1976