PLASMA DHA, DHAS AND CORTISOL-LEVELS AFTER INJECTION OF BETA-1-24 CORTICOTROPIN BETA-1-24 ACTH IN NORMAL ADULT WOMEN

  • 1 January 1981
    • journal article
    • research article
    • Vol. 42  (1) , 43-48
Abstract
Plasma DHA [dehydroepiandrosterone], DHAS [dehydroepiandrosterone sulfate] and cortisol levels were measured by radioimmunoassay before and after i.v. and i.m. injection of .beta. 1-24 ACTH. In 7 normal adult women, plasma cortisol and DHA levels rose sharply in response to .beta. 1-24 ACTH (0.25 mg) i.v. injection; plasma DHAS levels did not change significantly 30 and 120 min after the injection. In 9 normal adults women, the i.m. injection of Zn .beta. 1-24 ACTH (1 mg) caused a significant increase in both plasma cortisol, DHA and DHAS levels 8 and 24 h after the injection.