Clinical application of a flat-panel X-ray detector based on amorphous silicon technology: image quality and potential for radiation dose reduction in skeletal radiography.

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Abstract
The purpose of this study was to compare images obtained with a self-scanning, flat-panel X-ray detector based on amorphous silicon technology with conventional screen-film radiographs and to evaluate the possibility of radiation dose reduction in skeletal radiography. One hundred twenty patients were examined prospectively using a conventional screen-film system (speed, 400; detector dose, 2.5 microGy) and a prototype digital amorphous silicon detector (simulated speed, 400 and 800, n = 120; simulated speed, 1600, n = 40). The resulting 400 images were evaluated independently by six radiologists using a subjective five-point preference scale that rated overexposure, underexposure, contrast resolution, spatial resolution, and soft-tissue presentation. Image quality was ranked on a scale from 0 to 10 according to subjective criteria. Statistical significance of differences was determined using Student's t test and confidence intervals (95% confidence level). Comparison of conventional radiographs with digital images revealed a statistically significant preference for the digital system for soft-tissue presentation (speed 400 and 800) and visualization of osteoarthrotic changes (speed 400). A small but statistically significant preference for conventional images was found with respect to contrast and spatial resolution when digital speed was 800 or 1600; and the visibility of arthrosis at digital speed 1600, osteolysis at digital speed 800 and 1600, and fractures at digital speed 1600. The amorphous silicon-based system with a simulated speed of 400 provided images equivalent to screen-film radiographs. For clinical tasks such as routine follow-up studies, assessment of instability, or orthopedic measurements, a radiation dose reduction of up to 75% may be possible.