RESPONSE OF NASAL-MUCOSA TO ALLERGEN CHALLENGE MEASURED BY 2 DIFFERENT METHODS OF RHINOMANOMETRY

  • 1 January 1977
    • journal article
    • research article
    • Vol. 38  (4) , 263-267
Abstract
Nasal provocation tests with allergen (house dust 5.0 mg/ml or grass-pollen [Secale cereale, Dactylis glomerata, Lolium perenne, Anthoxanthum odoratum, Agrostis alba, Holcus lanatus, Phleum pratense, Cynosurus cristatus, Alopecurus pratensis] 10,000 Noon units/ml) were performed on patients suffering from perennial rhinitis or pollinosis. The changes of the nasal passages before and after allergen challenge were measured by 2 different methods, the rhinomanometry anterior (balloon) method, and the rhinomanometry posterior (V-P [volume-pressure]) method. No distinct differences were observed between results obtained by the 2 methods. Both are considered suitable and applicable for nasal provocation tests. For a satisfactory result using both techniques, the measurements should be made within at least 30 min, but preferably 60 min, after the allergen challenge.