Influence of Acetylcholine on Human Pulmonary Circulation under Normal and Hypoxic Conditions.
- 1 October 1956
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 93 (1) , 77-79
- https://doi.org/10.3181/00379727-93-22668
Abstract
Summary Acetylcholine infused into the main pulmonary artery caused a slight fall in pulmonary arterial pressure when the subject breathed ambient air, but a greater fall in pressure after pulmonary hypertension had been produced by hypoxia. The fall in pressure was associated with either a constant or an increased cardiac output. The evidence suggests that acetylcholine causes vasodilata-tion in the lungs and that this action is largely dependent on the pre-existing tone of the pulmonary vessels.Keywords
This publication has 3 references indexed in Scilit:
- The Pulmonary Vascular Responses to Short-Term Hypoxia in Human SubjectsCirculation, 1952
- ANOXIA AND HUMAN PULMONARY VASCULAR RESISTANCE 12Journal of Clinical Investigation, 1951
- THE INFLUENCE OF SHORT PERIODS OF INDUCED ACUTE ANOXIA UPON PULMONARY ARTERY PRESSURES IN MANAmerican Journal of Physiology-Legacy Content, 1947