Trisomy 8 in philadelphia chromosome (ph1)‐negative cells in the course of ph1‐positive chronic myelocytic leukemia
- 1 April 1992
- journal article
- case report
- Published by Wiley in Genes, Chromosomes and Cancer
- Vol. 4 (3) , 269-270
- https://doi.org/10.1002/gcc.2870040314
Abstract
A female patient with chronic myelocytic leukemia (CML) in chronic phase after busulfan and interferon treatment had four different cell lines in her bone marrow. In addition to cells with a normal karyotype there were cells with the Philadelphia chromosome (Ph1), cells with trisomy 8 and a Ph1, and cells with trisomy 8 as the sole anomaly.Keywords
This publication has 3 references indexed in Scilit:
- Prognostic significance of additional cytogenetic abnormalities at diagnosis of Philadelphia chromosome-positive chronic granulocytic leukemiaBlood, 1988
- The karyotype of blastic crisisCancer Genetics and Cytogenetics, 1987
- Cytogenetics of the myelodysplastic syndromesScandinavian Journal of Haematology, 1986