Scanning Mutagenesis of a Janus-faced Atracotoxin Reveals a Bipartite Surface Patch That Is Essential for Neurotoxic Function
Open Access
- 1 June 2002
- journal article
- Published by Elsevier in Journal of Biological Chemistry
- Vol. 277 (25) , 22806-22813
- https://doi.org/10.1074/jbc.m202297200
Abstract
No abstract availableKeywords
This publication has 44 references indexed in Scilit:
- Solution Structure of Ptu1, a Toxin from the Assassin Bug Peirates turpis That Blocks the Voltage-Sensitive Calcium Channel N-TypeBiochemistry, 2001
- Clockwise Domain Arrangement of the Sodium Channel Revealed by ¼-Conotoxin (GIIIA) Docking OrientationJournal of Biological Chemistry, 2001
- Genetic analysis of ion channel dysfunction in DrosophilaKidney International, 2000
- Anatomy of hot spots in protein interfacesJournal of Molecular Biology, 1998
- The Structure of the Potassium Channel: Molecular Basis of K + Conduction and SelectivityScience, 1998
- Predominant Interactions between μ-Conotoxin Arg-13 and the Skeletal Muscle Na+Channel Localized by Mutant Cycle AnalysisBiochemistry, 1998
- Structure-Function Relationships of ω-Conotoxin GVIAJournal of Biological Chemistry, 1997
- Combinatorial peptide libraries in drug design: lessons from venomous cone snailsTrends in Biotechnology, 1995
- Structure-Activity Analysis of a Conus Peptide Blocker of N-Type Neuronal Calcium ChannelsBiochemistry, 1995
- Intimations of potassium channel structure from a complete functional map of the molecular surface of charybdotoxinBiochemistry, 1994