Pain and nociception in the clinical context
- 19 February 1985
- journal article
- Published by The Royal Society in Philosophical Transactions of the Royal Society of London. B, Biological Sciences
- Vol. 308 (1136) , 219-226
- https://doi.org/10.1098/rstb.1985.0022
Abstract
Two subjects will be discussed: (i) the changes brought about in the central nervous system by a noxious input; (ii) certain states of consciousness in which human beings do not feel pain. Examples will be given of a pattern of neural activity being latent in the central nervous system after a period of localized pain. When this region is stimulated, even after a period of years, the previous pain is felt. Also, stimulation of the sensory cortex and thalamus in conscious patients shows permanent changes induced by constant pain. Studies from the literature are reported of human beings inducing trance states in themselves so as not to feel pain. In all of these states there is a great increase in sympathetic activity and an increase in the theta-activity in the electroencephalogram.Keywords
This publication has 3 references indexed in Scilit:
- Topographic reorganization of somatosensory cortical areas 3b and 1 in adult monkeys following restricted deafferentationNeuroscience, 1983
- Chronic changes in the response of cells in adult cat dorsal horn following partial deafferentation: The appearance of responding cells in a previously nonresponsive regionBrain Research, 1976
- The effect of hypnotic anaesthesia on cortical responsesJournal of Neurology, Neurosurgery & Psychiatry, 1964