Structure–activity relationships and enzyme inhibition of pantothenamide-type pantothenate kinase inhibitors

This publication has 19 references indexed in Scilit:

• A Pantothenate Kinase from Staphylococcus aureus Refractory to Feedback Regulation by Coenzyme A
  Journal of Biological Chemistry, 2005
• The Structure of the Pantothenate Kinase·ADP·Pantothenate Ternary Complex Reveals the Relationship between the Binding Sites for Substrate, Allosteric Regulator, and Antimetabolites
  Published by Elsevier ,2004
• Inhibitors of Pantothenate Kinase: Novel Antibiotics for Staphylococcal Infections
  Antimicrobial Agents and Chemotherapy, 2003
• Role of Feedback Regulation of Pantothenate Kinase (CoaA) in Control of Coenzyme A Levels in Escherichia coli
  Journal of Bacteriology, 2003
• The Antibiotic Activity of N-Pentylpantothenamide Results from Its Conversion to Ethyldethia-Coenzyme A, a Coenzyme A Antimetabolite
  Published by Elsevier ,2002
• A Missense Mutation in the fabB (β-Ketoacyl-Acyl Carrier Protein Synthase I) Gene Confers Thiolactomycin Resistance to Escherichia coli
  Antimicrobial Agents and Chemotherapy, 2002
• Strategies to Prevent and Control the Emergence and Spread of Antimicrobial-Resistant Microorganisms in Hospitals. A challenge to hospital leadership
  Published by American Medical Association (AMA) ,1996
• Enoyl-Acyl Carrier Protein Reductase (fabI) Plays a Determinant Role in Completing Cycles of Fatty Acid Elongation in Escherichia coli
  Journal of Biological Chemistry, 1995
• Use of R-Pantolactone in the Synthesis of L-TertLeucine Derivatives
  Synthetic Communications, 1994
• N1-(substituted) pantothenamides, antimetabolites of pantothenic acid
  Archives of Biochemistry and Biophysics, 1970