Arsenic Species Separation by IELC-ICP/OES: Arsenochoune Behavior

Abstract
The separation conditions and quantification of As(III), As(V), monomethylarsenate (MMA), dimethylarsinate (DMA), arsenobetaine (AsBet) and arsenocholine (AsChol) are studied by Liquid Chromatography (LC) coupled directlv to an Inductively Coupled Plasma Optical Emission Spectroscopy (ICP/OES) system. The separation conditions are optimized to improve the resolution of the six arsenic species. Arsenocholine shows a particular pattern of behaviour when phosphate is used as eluent: two peaks are observed in the chromatogram, thus a svstematic study assaving different pH and concentration of phosphate is carried out to improve resolution and analvsis time when the six arsenic compounds are analyzed in a mixture. Boric acid as mobile phase avoids the splitting of the arsenocholine peak and leads to a good separation of the six arsenic compounds. Detection limits are stablished for the six arsenic species.

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