Collagen corneal shields enhance penetration of topical prednisolone acetate
- 1 November 1989
- journal article
- research article
- Published by Wolters Kluwer Health in Journal of Cataract & Refractive Surgery
- Vol. 15 (6) , 625-628
- https://doi.org/10.1016/s0886-3350(89)80025-2
Abstract
We used an animal model to compare the corneal and aqueous penetration of topical prednisolone acetate 1% with and without the presence of a commercially available collagen corneal shield. A significant (P <.02) increase in penetration into cornea and aqueous humor at 30 minutes and 120 minutes was found in eyes with a collagen corneal shield in place. Increased concentrations were achieved by soaking the shield in prednisolone acetate for 15 minutes prior to application.This publication has 8 references indexed in Scilit:
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