Enhancement of antitumor effect of cytotoxic agents by bestatin.
- 1 January 1985
- journal article
- research article
- Published by Japan Antibiotics Research Association in The Journal of Antibiotics
- Vol. 38 (3) , 411-414
- https://doi.org/10.7164/antibiotics.38.411
Abstract
Bestatin enhanced the antitumor effects of mitomycin C, 5-fluorouracil and cis-dichlorodiammineplatinum against a syngeneic solid tumor of colon adenocarcinoma 26 in BALB/c mice. The enhancement was dependent on administration schedule. Bestatin administration after treatment with the cytotoxic agents was more effective than that made before the treatment.This publication has 10 references indexed in Scilit:
- Stimulation of cell-mediated immunity by bestatin correlates with reduction of bacterial persistence in experimental chronic Salmonella typhimurium infectionInfection and Immunity, 1984
- ABILITY OF THE IMMUNOMODULATING DIPEPTIDE BESTATIN TO ACTIVATE CYTO-TOXIC MONONUCLEAR PHAGOCYTES1983
- Current results of the screening program at the division of cancer treatment, national cancer institutePublished by Elsevier ,1981
- Inhibition of lymph node metastasis of P388 leukemia by bestatin in mice.The Journal of Antibiotics, 1981
- Mitogenic effect of bestatin on lymphocytes.The Journal of Antibiotics, 1980
- Effect of bestatin on mouse immune system and experimental murine tumors.The Journal of Antibiotics, 1980
- RESTORATION OF IMPAIRED IMMUNE FUNCTIONS OF AGED ANIMALS BY CHRONIC BESTATIN TREATMENT1979
- Inhibition of aminopeptidase B and leucine aminopeptidase by bestatin and its stereoisomerArchives of Biochemistry and Biophysics, 1976
- Aminopeptidase activities on the surface of mammalian cellsBiochimica et Biophysica Acta (BBA) - Enzymology, 1976
- Enhancement of delayed-type hypersensitivity by bestatin, an inhibitor of aminopeptidase B and leucine aminopeptidase.The Journal of Antibiotics, 1976