Naloxone administration in obsessive-compulsive disorder: report of two cases
- 1 September 1983
- journal article
- case report
- Published by American Psychiatric Association Publishing in American Journal of Psychiatry
- Vol. 140 (9) , 1219-1220
- https://doi.org/10.1176/ajp.140.9.1219
Abstract
Two patients with obsessive-compulsive disorder experienced an exacerbation of chronic obsessional doubt after double-blind, placebo-controlled administration of naloxone. Endogenous opiates may be involved in the pathogenesis of this symptom.Keywords
This publication has 2 references indexed in Scilit:
- The Psychopharmacological Treatment of Obsessive-Compulsive DisorderJournal of Clinical Psychopharmacology, 1981
- Enkephalin may mediate euphoria and drive-reduction rewardNature, 1977