Ascorbic Acid and Complement Function

Abstract
Summary: A correlation has been shown to exist between the concentration of ascorbic acid in the blood serum of guinea pigs and the complementing activity of the serum. In vivo, this parallelism holds true until a definite level of ascorbic acid is reached at about 1 mgm. per 100 cc. of serum. Serums treated in vitro with optimum quantities of ascorbic acid show a distinct rise of complementing activity and increased stability.

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