POSSIBLE SITES OF ORIGIN OF HUMAN-PLASMA RIBONUCLEASES AS EVIDENCED BY ISOLATION AND PARTIAL CHARACTERIZATION OF RIBONUCLEASES FROM SEVERAL HUMAN TISSUES
- 1 January 1978
- journal article
- research article
- Vol. 38 (1) , 88-93
Abstract
The RNase present in a number of human tissues, including heart, brain, lung and kidney, were purified, partially characterized and compared in their properties to the previously described RNases from human liver, spleen, pancreas and serum. The enzymes appeared to fall into 2 major classes: liver-spleen type RNase and plasma-type RNase. These 2 types of enzymes were present in varying proportions in all tissues examined. The extent to which the tissues studied possibly contribute to serum RNase levels is discussed.This publication has 10 references indexed in Scilit:
- The immunological characterization of several human ribonucleases by using primary binding testsBiochemical Journal, 1977
- Influence of Renal Insufficiency on Levels of Serum Ribonuclease in Patients With Multiple Myeloma 2JNCI Journal of the National Cancer Institute, 1977
- LEVELS OF SERUM RIBONUCLEASE AS AN INDICATOR OF RENAL-INSUFFICIENCY IN PATIENTS WITH LEUKEMIA1977
- Purification and properties of alkaline ribonuclease from human serumBiochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1976
- Elevated serum ribonuclease in patients with pancreatic cancer.Proceedings of the National Academy of Sciences, 1976
- Purification and properties of human acid-thermostable ribonucleases, and diagnosis of childhood pancreatic fibrosisClinica Chimica Acta; International Journal of Clinical Chemistry, 1976
- Research on Pancreatic RibonucleaseThe Journal of Biochemistry, 1964
- RIBONUCLEASE ACTIVITY AND CANCER1963
- Some Factors Which Affect the Enzymatic Digestion of Ribonucleic AcidJournal of Biological Chemistry, 1959
- Serum Ribonuclease ActivityJournal of Applied Physiology, 1958