A facile synthesis of 6‐alkoxy‐2,4‐diaryl‐5‐cyanopyridine
- 1 November 1989
- journal article
- research article
- Published by Wiley in Journal of Heterocyclic Chemistry
- Vol. 26 (6) , 1665-1673
- https://doi.org/10.1002/jhet.5570260629
Abstract
A new synthesis of substituted pyridine is reported. The base catalyzed reaction of substituted chalcones with malononitrile using sodium ethoxide in ethanol at room temperature afforded 2,4‐diaryl‐5‐cyano‐6‐ethoxypyridine. Similarly, 2,4‐diaryl‐5‐cyano‐6‐methoxypyridine have been prepared in presence of sodium methoxide in methanol as a catalyst.Keywords
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